Blockchain Press Releases
InSilicoTrials and Axoltis Pharma Collaborate to Advance Therapeutic Solutions for Neurological Disorders
MILAN, July 27, 2023 /PRNewswire/ — InSilicoTrials, a leading provider of artificial intelligence (AI) and simulation tools for drug and medical device development, has embarked on a collaborative partnership with Axoltis Pharma, a biopharmaceutical company committed to developing disease-modifying drugs for patients with high unmet medical needs in neurodegenerative and traumatic neurologic impairments. This strategic collaboration works to revolutionize our understanding of Central Nervous System (CNS) diseases and to optimize the clinical development plan of Axoltis’ drug candidate, NX210c, a promising 12-amino acid peptide derived from SCO-spondin.
The primary focus of this partnership is to utilize the InSilicoTrials’ platform and leverage its InSilicoNEURO suite, which encompasses a variety of mechanistic CNS models. More specifically, the models within InSilicoNEURO will be used to assess the impact of Axoltis’ drug candidate on virtual patients with different conditions, including Amyotrophic Lateral Sclerosis (ALS), Parkinson’s Disease and Multiple sclerosis (MS). Mechanistic CNS models are designed to simulate the physiological and pathological aspects of CNS disorders, providing insights into the disease mechanisms and potential therapeutic interventions. Integrating knowledge from various data sources, these models help researchers and clinicians understand the complex interactions within the CNS and contribute to the development of improved diagnostics and disease-modifying treatments for CNS disorders.
Neurodegenerative conditions are often characterized by several common features, including blood-brain barrier leakage, synaptic transmission deteriorations, and neuron apoptosis. Given that Axoltis drug candidate NX210c targets these features, the collaboration with InSilicoTrials holds great promise for supporting CNS functions in a wide range of neurological and neurodegenerative conditions. By utilizing the InSilicoTrials’ digital platform and leveraging Phase Ib clinical trial data and the preclinical package, the collaboration works to assess the relationship between NX210c dosing regimens, blood brain barrier repair and neurological function, biomarker concentrations, and ultimately clinical efficacy and safety endpoints, through computational modeling and simulation (CM&S) and AI techniques
Unlocking the potential of artificial intelligence and computational modeling, the two companies work to accelerate research and development, minimize costs, and optimize time utilization.
“We are thrilled to collaborate with Axoltis in our shared mission to advance therapeutic solutions for neurological disorders,” said Luca Emili, CEO of InSilicoTrials. “This partnership represents an exciting synergy between cutting-edge simulation technologies and innovative biotechnological advancements. Together, we aim to unlock new insights and develop groundbreaking treatments that will positively impact the lives of patients with neurologic impairments worldwide.”
Dr. Yann Godfrin, CEO of Axoltis stated: “We are very delighted to initiate this collaboration with InSilicoTrials and have the opportunity to optimize and accelerate our next clinical steps. Integrating their industry-leading AI and computational modeling solutions in the development plan of our promising disease-modifying drug will allow us to address the pressing challenges faced by individuals suffering from neurological disorders.“
InSilicoTrials is an emerging startup founded by a team of life science, cybersecurity and digital innovation experts, which aims to revolutionize healthcare through an innovative modeling & simulation platform. InSilicoTrials has created a vertical software solution that integrates cutting-edge AI and simulation tools with the goal of helping pharmaceutical, medtech companies and researchers develop new drugs more efficiently and at a lower cost by reducing the need for traditional, time-consuming, and expensive clinical trials.
Additionally, the solution contributes to the reduction, refinement, and replacement of in vitro, animal, and human testing methods. InSilicoTrials built up an ecosystem of more than 70 scientific collaborations, where computational models are developed with internationally recognized universities and research centers, offering access to the highest level of data security. With its cloud-based platform offering advanced M&S tools to perform in silico trials analyses, InSilicoTrials supports companies to integrate AI and simulation technology into their drug development workflows.
Axoltis Pharma is a French biopharmaceutical company dedicated to developing a first-in-class disease-modifying drug to treat patients with neurodegenerative or traumatic neurological disorders with high unmet medical needs. NX210c, an innovative and promising drug-candidate, is a small peptide derived from SCO-spondin, a glycoprotein essential for neurogenesis during embryogenesis.
This disease-modifying drug candidate has three main properties: recovery of blood brain barrier integrity, neuroprotection, and enhancement of neurotransmission. These properties are very useful in the treatment of multiple neurodegenerative diseases, especially as there is strong evidence that blood brain barrier dysfunction promotes disease progression from early stages of the disease.
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Blockchain Press Releases
Canaan Introduces Revolutionary Bitcoin Mining Heaters for Home and Personal Use in CES 2025
LAS VEGAS, Jan. 7, 2025 /PRNewswire/ — Canaan INC (NASDAQ: CAN), a leading blockchain hardware manufacturer, today announced the launch of the Avalon Mini 3 and Nano 3S in Las Vegas, CES. The two innovative Bitcoin mining devices are designed to democratize cryptocurrency mining for individuals and turning a home heating system into a crypto mining device.
Product Innovation
Canaan is redefining home cryptocurrency mining with two groundbreaking devices. The Avalon Mini 3, with a Hashrate of 37.5Th/s, offers a unique dual-purpose solution, combining efficient Bitcoin mining with home heating. The app-controlled operation and sleek, quiet design, provides a remarkably easy-to-use, energy-efficient solution for mining newcomers and enthusiasts.
The Avalon Nano 3S, which is upgraded from the widely-welcomed Avalon Nano 3, with a Hashrate of 6Th/s, complements this offering as an affordable, beginner-friendly Bitcoin mining device. Its compact and portable design alongside its low power consumption makes it ideal for individual users while supporting the broader goal of Bitcoin network decentralization.
Reimagining Technology Efficiency
The Avalon Mini 3 can simultaneously mine Bitcoin and warm living spaces, offering homeowners a unique way to offset energy costs and reduce environmental impact. This device gives users innovative access to heat recycling, turning the computational work of Bitcoin mining into a dual-purpose solution that provides both digital currency and home comfort.
“We are committed to making Bitcoin mining accessible to everyone,” said NG Zhang, CEO and founder of Canaan. “The Avalon Mini 3 and Avalon 3S represent our vision of user-friendly, practical mining solutions for the modern individual. We’re reimagining how technology can create value while minimizing environmental waste. The Avalon Mini 3’s ability to generate cryptocurrency while heating your home is a perfect example of our vision for sustainable, multi-purpose technology.”
Availability
Preorder Now at https://canaan.io/avalonhome
During the preorder period till the end of February 2025, the price for Avalon Nano 3S is USD249 and Avalon Mini 3 is USD899 while supplies last.
About Canaan Inc.
Canaan Inc. (NASDAQ: CAN), is a technology company focusing on ASIC high-performance computing chip design, chip research and development, computing equipment production, and software services. In 2013, under the leadership of Mr. Nangeng Zhang, founder and CEO, Canaan’s founding team shipped to its customers the world’s first batch of mining machines incorporating ASIC technology in Bitcoin’s history under the brand name Avalon.
Website: canaan.io
Media Contact: [email protected]
Telegram Group Official: https://t.me/Canaanio
X.com: https://x.com/canaanio
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DUBAI, UAE, Jan. 7, 2025 /PRNewswire/ — Bybit, the world’s second-largest cryptocurrency exchange by trading volume, has added the trending Solana-based AI token, AI16Z, to Bybit Spot on Jan. 6, 2025. The official listing came on the heels of AI16Z’s success on ByVotes, and was followed by a 24-hour gain of 47% after listing on Bybit.
AI16Z was the first ByVotes project to have garnered vast community support for Spot Listing on Bybit in 2025. Since the revamp of the platform, ByVotes has attracted a wave of quality projects from the niche to the high profile. Under the new mechanisms, the Bybit community now has a direct impact on choosing projects for listing on the exchange by casting their votes of confidence via ByVotes. A number of fan favorites made their mark on ByVotes in the past year, including AI-themed LUNAI with a record number of 512 million votes, and other iconic memecoins such as CHILLGUY, LUCE, NEIROCTO, and HPOS10I.
Users may still unlock exclusive rewards trading AI16Z on Bybit Spot in two events: Token Splash and Puzzle Hunt, each with a 50,000 AI16Z prize pool. The token attracted over 72,000 Bybit users in the pre-listing round of community votes on ByVotes, and received some 300,000,000 votes in the two-day voting period.
AI16Z on Bybit Spot
Bybit users have the opportunities to get more out of their AI16Z trades on Bybit:
- AI16Z Token Splash: the newly listed token comes with a 50,000 AI16Z prize pool for both new and seasoned traders. From now to Jan. 20, 2025, the first 3,500 eligible new users to successfully complete two simple tasks will receive 10 AI16Z each. In addition, existing users stand to earn up to 1,000 AI16Z by trading the token.
- AI16Z Puzzle Hunt: A new puzzle hunt for 50,000 AI16Z has kicked off on Bybit. From now to Jan. 21, Bybit users may earn or exchange puzzle pieces for a chance to win from the lucky draw, and the luckiest first 200 users to complete the entire puzzle will get to claim 50 AI16Z.
Registration is required for both events, terms and conditions apply. AI16Z are also available for trades via Bybit Spot Grid Bots.
Since Dec. 25, 2024, the native token of the world’s first investment DAO led by AI agents has doubled in market cap after the listing, well past the $2 billion mark as of this week. Leading the way as blockchain’s decentralized answer to traditional VC, the DAO fuses AI’s advanced power with crypto’s meme culture to raise the bar for intelligent decentralized governance. Powered by the Eliza Framework, the face of the ai16z is AI Marc who is a brainchild of Marc Andreessen.
#Bybit / #TheCryptoArk
Bybit is the world’s second-largest cryptocurrency exchange by trading volume, serving a global community of over 60 million users. Founded in 2018, Bybit is redefining openness in the decentralized world by creating a simpler, open and equal ecosystem for everyone. With a strong focus on Web3, Bybit partners strategically with leading blockchain protocols to provide robust infrastructure and drive on-chain innovation. Renowned for its secure custody, diverse marketplaces, intuitive user experience, and advanced blockchain tools, Bybit bridges the gap between TradFi and DeFi, empowering builders, creators, and enthusiasts to unlock the full potential of Web3. Discover the future of decentralized finance at Bybit.com.
For more details about Bybit, please visit Bybit Press
For media inquiries, please contact: [email protected]
For updates, please follow: Bybit’s Communities and Social Media
Discord | Facebook | Instagram | LinkedIn | Reddit | Telegram | TikTok | X | Youtube
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Blockchain Press Releases
Get Ready for Bybit’s ‘Keynote with Ben’ Livestream: Unveiling 2025 Vision and Exclusive Prize Pool
DUBAI, UAE, Jan. 7, 2025 /PRNewswire/ — Bybit, the world’s second-largest cryptocurrency exchange by trading volume, is gearing up to captivate audiences with its highly anticipated livestream event, Keynote with Ben: In the Driving Seat to the Moon — Beat the Unknown. The event promises to spotlight Bybit’s remarkable journey, its vision for 2025 and beyond, and a series of groundbreaking innovations that redefine the digital finance landscape.
Scheduled for Jan. 21, 2025, at 8 a.m. UTC, the livestream will feature Bybit’s CEO Ben Zhou delivering insights into the future of Web3, Bybit’s ecosystem expansion, and pioneering advancements in wealth management. With a commitment to shaping the next era of decentralized finance, Bybit aims to inspire and inform both its loyal community and newcomers alike.
Exciting Rewards Await
In conjunction with the keynote, Bybit is launching an exclusive campaign running from now to Jan. 21, 2025. Participants have the opportunity to win a share from a generous 5,250 prize pool in combined rewards, including tokens and P2P coupons. The rewards will be distributed through various activities:
- New User Exclusive: New users who sign up and subscribe to the event early can claim a 5 USDT reward on top of Bybit’s 20 USDT sign-up bonus. This offer is limited to the first 150 participants.
- Spread the Word: By sharing the livestream link on social media and submitting proof of their posts, 100 lucky participants will receive a 5 USDT spot airdrop.
- Trade and Win During the Livestream: Participants who trade at least 50 USDT during the livestream can share a 3,300 CHILLGUY prize pool, while new users depositing 100 USDT or more will compete for a 200 GRASS token prize pool.
- Ask and Earn: By submitting thought-provoking questions through the livestream page, 25 standout participants will win 20 USDT P2P coupons, sharing a total prize of $500.
Unveiling a Bullish Vision
Bybit’s 2025 roadmap includes ambitious milestones and transformative strategies designed to empower its users in the evolving Web3 ecosystem. Attendees of the keynote can expect firsthand insights into the company’s accomplishments and its forward-looking initiatives.
The keynote will feature a retrospective on Bybit’s significant milestones achieved in 2024, the unveiling of new ecosystem expansions, and an exploration of cutting-edge Web3 innovations. Additionally, attendees can look forward to announcements about advanced wealth management solutions designed to empower users in a decentralized future.
Bybit invites its community and beyond to join this milestone event, where vision meets action, and opportunities for rewards are plentiful. While the livestream is sure to inspire, the accompanying campaign ensures tangible benefits for those participating in Bybit’s ongoing journey to the moon.
#Bybit / #TheCryptoArk / #BybitLivestream
Bybit is the world’s second-largest cryptocurrency exchange by trading volume, serving a global community of over 60 million users. Founded in 2018, Bybit is redefining openness in the decentralized world by creating a simpler, open and equal ecosystem for everyone. With a strong focus on Web3, Bybit partners strategically with leading blockchain protocols to provide robust infrastructure and drive on-chain innovation. Renowned for its secure custody, diverse marketplaces, intuitive user experience, and advanced blockchain tools, Bybit bridges the gap between TradFi and DeFi, empowering builders, creators, and enthusiasts to unlock the full potential of Web3. Discover the future of decentralized finance at Bybit.com.
For more details about Bybit, please visit Bybit Press
For media inquiries, please contact: [email protected]
For updates, please follow: Bybit’s Communities and Social Media
Discord | Facebook | Instagram | LinkedIn | Reddit | Telegram | TikTok | X | Youtube
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